Working out can reduce pain and fatigue in women with advanced breast cancer, according to a new study.
New research found that taking part in an exercise program reduced pain and fatigue, and improved quality of life for people with metastatic breast cancer.
Metastatic cancer is cancer that has spread to other parts of the body, and the researchers say that their findings provide strong evidence that all patients with this type of cancer should be offered exercise as part of their package of treatment and care.
Dr. Anouk Hiensch, of the University Medical Centre Utrecht in The Netherlands, said: “Although there’s been quite a lot of research looking at exercise for people with early-stage cancer, we have seen very little research on exercise in patients with more advanced disease.
“Patients with metastatic cancer often undergo continuous treatment that aims to prolong their life. Thanks to these treatments, many patients with metastatic cancer live longer, but many also report a deteriorating quality of life over time.
“We therefore need supportive care strategies, like exercise, that make the lives of these patients better.”
The trial included 357 patients with metastatic breast cancer with an average age of around 55 years.
Patients were recruited at one of eight cancer centers in Germany, Poland, Spain, Sweden, The Netherlands and Australia.
Of these patients, 178 were randomly selected to take part in a nine-month exercise program alongside their usual care with the other 179 given their usual care.
The exercise program consisted of twice-weekly personalized training with resistance, aerobic and balance exercises overseen by a physiotherapist or exercise physiologist.
At the start of the study and after three, six, and nine months, researchers asked patients about their levels of fatigue and their quality of life, including any pain they were suffering.
The results, to be presented at the 14th European Breast Cancer Conference in Milan, Italy, show that patients who took part in the exercise program suffered less fatigue and had better quality of life.
The biggest improvements were for women under the age of 50 and those suffering pain at the beginning of the study.
The researchers therefore recommend that exercise programs should be looked into as a part of treatment plans for advanced cancer patients.
Dr. Hiensch said: “Based on these findings, we recommend supervised exercise for all patients with metastatic breast cancer – particularly those who are experiencing pain – as part of their standard care.
“If patients are interested in exercising, I recommend talking to their doctor or nurse first and looking for an exercise trainer who is trained in helping cancer patients.
“We don’t know exactly why exercise helps cancer patients who are suffering from pain, but we think it could be because exercise reduces inflammation.
"We have collected blood samples from our trial participants and studying these samples may tell us more.”
The team is also conducting a cost-effectiveness analysis to help convince policymakers and health insurers to fund exercise programs for patients.
Professor Michail Ignatiadis from the Institut Jules Bordet in Brussels, Belgium added: “This research is good news for patients with advanced breast cancer because it shows that they can enjoy a better quality of life with less fatigue and pain if they take part in an exercise program as part of their package of treatment and care.
“People with metastatic cancer cannot always be cured of their disease but they can live for many months or years, so ensuring they have the best possible quality of life is absolutely vital.”
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