A computer has been trained to spot whether someone will have a heart attack in the next year, from routine eye tests.
The AI (artificial intelligence) system opens the door to a cheap and simple screening program for the world's number one killer.
It predicts patients at risk of a heart attack in the next 12 months - and is up to 80 percent accurate.
The breakthrough adds to evidence our peepers are windows into overall health.
Project supervisor Professor Alex Frangi, of the University of Leeds, said: "Cardiovascular diseases, including heart attacks, are the leading cause of early death worldwide and the second-largest killer in the UK.
"This causes chronic ill-health and misery worldwide. This technique opens up the possibility of revolutionizing the screening of cardiac disease.
"Retinal scans are comparatively cheap and routinely used in many optician practices.
"As a result of automated screening, patients who are at high risk of becoming ill could be referred to specialist cardiac services.
"The scans could also be used to track the early signs of heart disease."
The retina is a small membrane at the back of the eye containing light-sensitive cells.
Doctors have recognized changes to the tiny blood vessels suggest vascular disease - including heart problems.
An advanced type of AI known as 'deep learning' was used to 'teach' the machine to automatically read more than 5,000 scans.
They were taken during visits to opticians' or eye clinics. Participants were members of the UK Biobank which is tracking the health of half a million Britons.
Deep learning is a complex series of algorithms that enable machines to make forecasts based on patterns in data.
The technique described in the journal Nature Machine Intelligence could revolutionize heart therapy, say the international team.
It was correct 70 to 80 percent of the time - offering hope of a second referral mechanism for in-depth cardiovascular investigation.
Co-author Professor Chris Gale, a consultant cardiologist at Leeds Teaching Hospitals NHS Trust, said: “The AI system has the potential to identify individuals attending routine eye screening who are at higher future risk of cardiovascular disease, whereby preventative treatments could be started earlier to prevent premature cardiovascular disease."
It identified associations between pathology in the retina and changes in the patient's heart.
Once the image patterns were learned, the AI system could estimate the size and pumping efficiency of the left ventricle from retinal scans alone.
This is one of the heart's four chambers. An enlarged ventricle is linked with an increased risk of heart disease.
The computer combined the estimated size of the left ventricle and its pumping efficiency with basic demographic data like age and sex.
Currently, such information is determined with MRI (magnetic resonance imaging) or echocardiography scans of the heart.
The diagnostic tests are expensive and are often only available in a hospital.
They are inaccessible for people in countries with less well-resourced healthcare systems.
They also increase healthcare costs and waiting times in wealthy nations.
Co-author Sven Plein, of the British Heart Foundation who is professor of cardiovascular imaging at Leeds said: "The AI system is an excellent tool for unraveling the complex patterns that exist in nature.
"That is what we have found here – the intricate pattern of changes in the retina linked to changes in the heart."
Last week a similar study by an Australian-led team identified a link between biological aging of the retina and mortality.
Those whose retina was 'older' than their actual years were up to 67 percent more likely to die over the next decade.
The analysis was based on almost 47,000 members of the UK Biobank aged 40 to 69.
Cardiovascular disease claims 17 million lives a year - including 160,000 in the UK.
Stories and infographics by ‘Talker Research’ are available to download & ready to use. Stories and videos by ‘Talker News’ are managed by SWNS. To license content for editorial or commercial use and to see the full scope of SWNS content, please email [email protected] or submit an inquiry via our contact form.
We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept All”, you consent to the use of ALL the cookies. However, you may visit "Cookie Settings" to provide a controlled consent.
This website uses cookies to improve your experience while you navigate through the website. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may affect your browsing experience.
Necessary cookies are absolutely essential for the website to function properly. These cookies ensure basic functionalities and security features of the website, anonymously.
Cookie
Duration
Description
__hssc
1 hour
HubSpot sets this cookie to keep track of sessions and to determine if HubSpot should increment the session number and timestamps in the __hstc cookie.
__hssrc
session
This cookie is set by Hubspot whenever it changes the session cookie. The __hssrc cookie set to 1 indicates that the user has restarted the browser, and if the cookie does not exist, it is assumed to be a new session.
_GRECAPTCHA
5 months 27 days
Google Recaptcha service sets this cookie to identify bots to protect the website against malicious spam attacks.
cookielawinfo-checkbox-advertisement
1 year
Set by the GDPR Cookie Consent plugin, this cookie records the user consent for the cookies in the "Advertisement" category.
cookielawinfo-checkbox-analytics
11 months
This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Analytics".
cookielawinfo-checkbox-functional
11 months
The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional".
cookielawinfo-checkbox-necessary
11 months
This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-others
11 months
This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Other.
cookielawinfo-checkbox-performance
11 months
This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Performance".
CookieLawInfoConsent
1 year
CookieYes sets this cookie to record the default button state of the corresponding category and the status of CCPA. It works only in coordination with the primary cookie.
rc::a
never
This cookie is set by the Google recaptcha service to identify bots to protect the website against malicious spam attacks.
rc::b
session
This cookie is set by the Google recaptcha service to identify bots to protect the website against malicious spam attacks.
rc::c
session
This cookie is set by the Google recaptcha service to identify bots to protect the website against malicious spam attacks.
rc::f
never
This cookie is set by the Google recaptcha service to identify bots to protect the website against malicious spam attacks.
ts
1 year 1 month 1 day
PayPal sets this cookie to enable secure transactions through PayPal.
usprivacy
1 year 1 month
This is a consent cookie set by Dailymotion to store the CCPA consent string (mandatory information about an end-user being or not being a California consumer and exercising or not exercising its statutory right).
viewed_cookie_policy
11 months
The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features.
Cookie
Duration
Description
__cf_bm
30 minutes
Cloudflare set the cookie to support Cloudflare Bot Management.
li_gc
5 months 27 days
Linkedin set this cookie for storing visitor's consent regarding using cookies for non-essential purposes.
lidc
1 day
LinkedIn sets the lidc cookie to facilitate data center selection.
UserMatchHistory
1 month
LinkedIn sets this cookie for LinkedIn Ads ID syncing.
v1st
1 year 1 month 1 day
The v1st cookie is set by TripAdvisor to collect details about how visitors use the website, by displaying user reviews, awards and information received on the TripAdvisor community.
yt-player-bandwidth
never
The yt-player-bandwidth cookie is used to store the user's video player preferences and settings, particularly related to bandwidth and streaming quality on YouTube.
yt-player-headers-readable
never
The yt-player-headers-readable cookie is used by YouTube to store user preferences related to video playback and interface, enhancing the user's viewing experience.
yt-remote-cast-available
session
The yt-remote-cast-available cookie is used to store the user's preferences regarding whether casting is available on their YouTube video player.
yt-remote-cast-installed
session
The yt-remote-cast-installed cookie is used to store the user's video player preferences using embedded YouTube video.
yt-remote-fast-check-period
session
The yt-remote-fast-check-period cookie is used by YouTube to store the user's video player preferences for embedded YouTube videos.
yt-remote-session-app
session
The yt-remote-session-app cookie is used by YouTube to store user preferences and information about the interface of the embedded YouTube video player.
yt-remote-session-name
session
The yt-remote-session-name cookie is used by YouTube to store the user's video player preferences using embedded YouTube video.
ytidb::LAST_RESULT_ENTRY_KEY
never
The cookie ytidb::LAST_RESULT_ENTRY_KEY is used by YouTube to store the last search result entry that was clicked by the user. This information is used to improve the user experience by providing more relevant search results in the future.
Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors.
Cookie
Duration
Description
_gat
1 minute
Google Universal Analytics sets this cookie to restrain request rate and thus limit data collection on high-traffic sites.
_p_hfp_client_id
less than a minute
Elfsight sets this cookie to implement social platforms on the website and enables the social platforms to track the users by assigning them a specific ID.
dmvk
session
The dmvk cookie is set by Dailymotion to record data of visitor behaviour on the website.
SRM_B
1 year 24 days
Used by Microsoft Advertising as a unique ID for visitors.
Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc.
Cookie
Duration
Description
__hstc
6 months
Hubspot set this main cookie for tracking visitors. It contains the domain, initial timestamp (first visit), last timestamp (last visit), current timestamp (this visit), and session number (increments for each subsequent session).
_clck
1 year
Microsoft Clarity sets this cookie to retain the browser's Clarity User ID and settings exclusive to that website. This guarantees that actions taken during subsequent visits to the same website will be linked to the same user ID.
_clsk
1 day
Microsoft Clarity sets this cookie to store and consolidate a user's pageviews into a single session recording.
_fbp
3 months
Facebook sets this cookie to display advertisements when either on Facebook or on a digital platform powered by Facebook advertising after visiting the website.
_ga
1 year 1 month 4 days
Google Analytics sets this cookie to calculate visitor, session and campaign data and track site usage for the site's analytics report. The cookie stores information anonymously and assigns a randomly generated number to recognise unique visitors.
_ga_*
1 year 1 month 4 days
Google Analytics sets this cookie to store and count page views.
_gat_gtag_UA_*
1 minute
Google Analytics sets this cookie to store a unique user ID.
_gcl_au
3 months
Google Tag Manager sets the cookie to experiment advertisement efficiency of websites using their services.
_gid
1 day
Google Analytics sets this cookie to store information on how visitors use a website while also creating an analytics report of the website's performance. Some of the collected data includes the number of visitors, their source, and the pages they visit anonymously.
AnalyticsSyncHistory
1 month
Linkedin set this cookie to store information about the time a sync took place with the lms_analytics cookie.
CLID
1 year
Microsoft Clarity set this cookie to store information about how visitors interact with the website. The cookie helps to provide an analysis report. The data collection includes the number of visitors, where they visit the website, and the pages visited.
CONSENT
2 years
YouTube sets this cookie via embedded YouTube videos and registers anonymous statistical data.
hubspotutk
6 months
HubSpot sets this cookie to keep track of the visitors to the website. This cookie is passed to HubSpot on form submission and used when deduplicating contacts.
ln_or
1 day
Linkedin sets this cookie to registers statistical data on users' behaviour on the website for internal analytics.
MR
7 days
This cookie, set by Bing, is used to collect user information for analytics purposes.
SM
session
Microsoft Clarity cookie set this cookie for synchronizing the MUID across Microsoft domains.
Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. These cookies track visitors across websites and collect information to provide customized ads.
Cookie
Duration
Description
ANONCHK
10 minutes
The ANONCHK cookie, set by Bing, is used to store a user's session ID and verify ads' clicks on the Bing search engine. The cookie helps in reporting and personalization as well.
bcookie
1 year
LinkedIn sets this cookie from LinkedIn share buttons and ad tags to recognize browser IDs.
bscookie
1 year
LinkedIn sets this cookie to store performed actions on the website.
fr
3 months
Facebook sets this cookie to show relevant advertisements by tracking user behaviour across the web, on sites with Facebook pixel or Facebook social plugin.
IDE
1 year 24 days 1 minute
Google DoubleClick IDE cookies store information about how the user uses the website to present them with relevant ads according to the user profile.
li_sugr
3 months
LinkedIn sets this cookie to collect user behaviour data to optimise the website and make advertisements on the website more relevant.
muc_ads
1 year 1 month 4 days
Twitter sets this cookie to collect user behaviour and interaction data to optimize the website.
MUID
1 year 24 days
Bing sets this cookie to recognise unique web browsers visiting Microsoft sites. This cookie is used for advertising, site analytics, and other operations.
personalization_id
1 year 1 month 4 days
Twitter sets this cookie to integrate and share features for social media and also store information about how the user uses the website, for tracking and targeting.
test_cookie
15 minutes
doubleclick.net sets this cookie to determine if the user's browser supports cookies.
ttwid
1 year
Tiktok sets this cookie to keep track of user authentication and session information.
VISITOR_INFO1_LIVE
5 months 27 days
YouTube sets this cookie to measure bandwidth, determining whether the user gets the new or old player interface.
VISITOR_PRIVACY_METADATA
6 months
YouTube sets this cookie to store the user's cookie consent state for the current domain.
YSC
session
Youtube sets this cookie to track the views of embedded videos on Youtube pages.
yt-remote-connected-devices
never
YouTube sets this cookie to store the user's video preferences using embedded YouTube videos.
yt-remote-device-id
never
YouTube sets this cookie to store the user's video preferences using embedded YouTube videos.
yt.innertube::nextId
never
YouTube sets this cookie to register a unique ID to store data on what videos from YouTube the user has seen.
yt.innertube::requests
never
YouTube sets this cookie to register a unique ID to store data on what videos from YouTube the user has seen.